P enisola Sorrentina is an Italian DOC title used for wines from the Sorrento Peninsula, in the Campania region of south-west Italy. The peninsula, which extends into the Tyrrhenian Sea on the southern side of Bay of Naples, is famous for its spectacular landscape and rugged coastline.

The land here is covered with small valleys and hillsides that create a patchwork of potential vineyard locations (not all of them easily accessible, however). The area's temperate, maritime-influenced climate and high sunshine levels create an ideal growing environment for grape vines.

The official Penisola Sorrentina wine production area contains three sub-zones: Gragnano, Lettere and Sorrento. The former pair are known for their lively, sparkling red wines (both dry and sweet), while Sorrento is better known for its still, dry table wines (both white and red).

The ancient Falanghina variety plays the leading role in the DOC's standard white wine, joined by Biancolella and Greco Bianco. The red wines are based on Piedirosso, supported by Aglianico and Sciascinoso (Olivella). These are the same grapes used in the sparkling red Rosso Frizzante Naturale.

For Penisola Sorrentina wines to be labeled with the name of their sub-zone (Gragnano, Lettere or Sorrento) their potential alcohol must be 1 percent more than the basic DOC wines. The red wines of this area have been described by some wine experts as "the Beaujolais of Campania".

This area wine style was a favorite of Pope Paul III (1468–1549), who, according to the writings of Saint Lancerio, described it as "a delicate drink"..